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Engin Umut Akkaya

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Professor   Supervisor of Doctorate Candidates   Supervisor of Master's Candidates  

Scientific Research

  • Prof. Engin U. Akkaya,his research interests are activatable photodynamic photosensitizers, altering photodynamic action toward novel cancer drugs, and information processing (smart) therapeutic agents and molecular probes. 

  • LIST OF PUBLICATIONS IN REVERSE CHRONOLOGICAL ORDER

    (Prof. Dr. Engin U. Akkaya)

     

                2019

    116.    Ucar, E.; Xi, D.; Seven, O., Kaya, C.; Peng, X. J., Sun, W., Akkaya, E. U. “ “Off-On” Switching of Intracellular Singlet Oxygen Release Under Biocompatible Conditions” Chem. Commun. 2019, 0000 DOI 10.1039/c9cc06231a

     

    115.     Turksoy, A.; Yildiz, D.; Akkaya, E. U. “Photosensitization and Controlled Photosensitization with Bodipy dyes” Coord. Chem. Rev. 2019, 379, 47-64.

     

    114.     Ucar, E.; Seven, O.; Lee, D.; Kim, G.; Yoon, J.; Akkaya, E. U. “Selectivity in Photodynamic Action: Higher Activity of Mitochondria Targeting Photosensitizers in Cancer Cells” ChemPhotoChem 2019, 3, 129-132


    2018

    113.     Yesilgul, N., Seven, O., Guliyev, R., Akkaya, E. U. J. Org. Chem. 2018, 83, 13228-13232.

     

    112.     Kolemen, S., Akkaya, E. U. "Reaction-based Bodipy probes for bio-imaging" Coord. Chem. Rev. 2018, 354, 121-134.

     

    111.    Turan, I. S., Gunaydin, G., Ayan, S., Akkaya, E. U. “Molecular Demultiplexer as a Terminator Automaton" Nat. Commun. 2018, 9, 805.

     

    110.    Erbas-Cakmak, S., Kolemen, S., Sedgwick, A. C., Gunnlaugsson, T., James, T. D., Yoon, J., Akkaya, E. U. “Molecular Logic gates: the past, present and future” Chem. Soc. Rev. 2017, 47, 2228-2248.


    2017

    109.    Wu, D., Sedgwick, A. C., Gunnlaugsson, T., Akkaya, E. U., Yoon, J., James, T. D., “Fluorescent Chemosensors: the past, present and future” Chem. Soc. Rev. 2017, 46, 7105-7123.

     

    108.     Akkaya, E. U., Katz, E.; Pischel, U. ChemPhysChem, 2017, 18, 1665-1666.


     107.          Ozdemir, T.; Lu, Y.-C.; Kolemen, S.; Tanrıverdi-Ecik, E.; Akkaya, E. U. “Generation of Singlet Oxygen by Persistent Luminescent Nanoparticle-Photosensitizer Conjugates:  A proof of Principle for Photodynamic Therapy without Light" ChemPhotoChem 2017, 1, 183-187.  


    106.    Li, X., Kolemen, S., Yoon, J. and Akkaya, E. U.Activatable Photosensitizers: Agents for Selective Photodynamic Therapy", Adv. Funct. Mater., 2017, 27, 1604053.

     

    105.    Yesilgul, N.; Uyar, T. B.; Seven, O.; Akkaya, E. U. “Singlet Oxygen Generation with Chemical Excitation of an Erythrosine-Luminol Conjugate" ACS Omega, 2017, 2, 1367–1371.

     

                104.          Turan, I. S.; Seven, O.; Ayan, S.; Akkaya, E. U. “Amplified Chemiluminescence Signal for Sensing Fluoride Ions" ACS Omega, 2017, 2, 3291–3295.

    2016

     

    103.    Cebula, M.; Turan, I. S.; Sjödin, B.; Thulasingam, M.; Brock, J.; Chmyrov, V.; Widengren, J.; Abe, H.; Mannervik, B.; Haeggström, J. Z.; Rinaldo-Matthis, A.; Akkaya, E. U.; Morgenstern, R. “Catalytic Conversion of Lipophilic Substrates by Phase constrained Enzymes in the Aqueous or in the Membrane Phase” Sci. Rep., 2016, 6, 38316.

     

    102.    Ozdemir, T.; Bila, J. L.; Sozmen, F.; Yildirim, L. T.; Akkaya, E.U.Orthogonal Bodipy Trimers as Efficient Photosensitizers for Photodynamic Action" Org. Lett. 2016, 18, 4821–4823.

     

           101.      Kolemen, S.; Ozdemir, T.; Lee, D. Kim, G. M.; Karatas, T.; Yoon, J.; Akkaya, E.

               U. “Remote Controlled Release of Singlet Oxygen by the Plasmonic Heating of    Gold Nanorods: Towards a Paradigm Change in Photodynamic Therapy"Angew.  Chem.   Int. Ed. 2016, 55, 3606–3610.

     

            100.      Turan, I. S.; Yildiz, D.; Turksoy, A.; Gunaydin, G.; Akkaya, E. U.A     Bifunctional        Photosensitizer for Enhanced Fractional Photodynamic Therapy:       Singlet Oxygen Generation in the                     Presence and Absence of Light” Angew.     Chem. Int. Ed. 2016,        55, 2875-2878.

     

             99.  Kilic, B.; Yesilgul, N.; Polat,  V.; Gercek, Z.; Akkaya, E. U. Bodipy-based     photosensitizers with long alkyl tails at the meso position: efficient singlet oxygen  generation in Cremophor-EL micelles,                     Tetrahedron Lett., 2016, 57, 1317-1320.

     

             98.        Turan, I, S.; Yilmaz, O.; Karatas, B.; Akkaya, E. U. “A sensitive and selective  chemiluminogenic probe for palladium” RSC Adv. 20155, 34535-34540.

        

             97.        Erbas-Cakmak, S.; Cakmak, F. P.; Topel, S. D.; Uyar, T. B.; Akkaya, E. U.   “Selective photosensitization through an and logic response: optimization of the  pH and glutathione response of activatable photosensitizers” Chem. Commun  2015, 12258-12261.

        

          96.        Kölemen, S.; Işık, M.; Kim, G. M.; Kim, D.; Geng, H.; Buyuktemiz, M; Karatas,  T.; Zhang, X.-F.; Dede, Y.; Yoon, J.; Akkaya, E. U. "Intracellular Modulation of  Excited State Dynamics in a Chromophore Dyad: Differential Enhancement of  Photocytotoxicity Targeting Cancer Cells" Angew. Chem. Int. Ed., 201554, 5340- 5344. FRONT COVER

       

    95.       T. Özdemir, Z. Köstereli, R. Guliyev, S. Yalçın, Y. Dede, E.U. Akkaya, "Ion Responsive Near-IR Bodipy Dyes: Two Isomers, Two Different Signals," RSC Advances, vol. 4, 14915-14918 (2014)


    94.       T. Özdemir, F. Sözmen, S. Mamur, T. Tekinay, E.U. Akkaya, "Fast Responding and Selective Near-IR Bodipy Dye for Hydrogen Sulfide Sensing," Chem. Commun., vol. 50, 5455-5457 (2014)


    93.       A. Atılgan, E. T. Eçik, R. Guliyev, T. B. Uyar, S. Erbaş-Çakmak, E.U. Akkaya, "Near-IR Triggered, Remote-Controlled Release of Metal Ions: A Novel Strategy for Caged Ions," Angew. Chem.-Int. Ed., 53, 10678-10681 (2014)


    92.       E. Ertem, A. Bekdemir, A. Atılgan, E.U. Akkaya, "Near IR Absorbing Bodipy-functionalized SPIONs: A Potential Magnetic Nanoplatform for Diagnosis and Therapy," Pure and Applied Chemistry, vol. 86, 899-903 (2014)


    91.       S. Erbaş-Çakmak, E.U. Akkaya, "Toward Singlet Oxygen Delivery at a Measured Rate: A Self-reporting Photosensitizer," Org. Lett., vol. 16, 2946-2949 (2014)


    90.       S. D. Topel, G. T. Cin, E.U. Akkaya, "Near IR Excitation of Heavy-atom Free Photosensitizers Through the Intermediacy of Upconverting Nanoparticles," Chem. Commun., 50, pp. 8896-8899 (2014)


    89.       S. Kölemen, Y. Çakmak, T. Özdemir, S. Erten-Ela, M. Büyüktemiz, Y. Dede, E.U. Akkaya, "Design and Synthesis of Bodipy Derivatives for Bulk Heterojunction Solar Cells," Tetrahedron, vol. 70, 6229-6234 (2014)


    88.       Y. Çakmak, T. Nalbantoğlu, T. Durgut, E.U. Akkaya, "PEGylated Calix[4]arene as a Carrier for a Bodipy-based Photosensitizer," Tetrahedron Lett., vol. 45, 538-540 (2014)


    87.       F. Sözmen, S. Kölemen, H.-O. Kumada, M. Ono, H. Saji, E.U. Akkaya, "Designing Bodipy-based Probes for Fluorescence Imaging of beta-amyloid Plaques," RSC Adv., vol. 4, 51032-51037 (2014)


    86.       I.S. Turan, E.U. Akkaya, "Chemiluminescence Sensing of Fluoride Ions Using a Self-Immolative Amplifier," Org. Lett., 16, 1680-1683 (2014)


    85.       E. Tanriverdi-Ecik, A. Atilgan, R. Guliyev, T.B. Uyar, A. Gumus, E.U. Akkaya, "Modular logic gates: cascading independent logic gates via metal ion signals," Dalton Transactions, vol. 43, 67-70 (2014) . JOURNAL COVER


    84.       S. Kolemen, Y. Cakmak, Z. Kostereli, E.U. Akkaya, “Atropisomeric Dyes: Axial Chirality in Orthogonal BODIPY Oligomers," Org. Lett., vol. 16, 660-663 (2014)


    83.       M. Isik, R. Guliyev, S. Kolemen, Y. Altay, B. Senturk, T. Tekinay, E.U. Akkaya, "Designing an Intracellular Fluorescent Probe for Glutathione: Two Modulation Sites for Selective Signal Transduction," Org. Lett., vol. 16, 3260-3263 (2014)


                82.  I. S. Turan,  F. P. Çakmak, D. C. Yıldırım, R. Çetin-Atalay, E.U. Akkaya, "Near-IR Absorbing BODIPY Derivatives as Glutathione-Activated Photosensitizers for Selective Photodynamic Action,"  Chem. Eur. J., 20, 16088-16092 (2014)


    81.       Erbas-Cakmak, S.; Akkaya, E.U. “Cascading of Molecular Logic Gates for Advanced Functions: A Self-Reporting, Activatable Photosensitizer” Angew. Chem. Int. Ed. 2013, 52, 11364-11368.


    80.       Buyukcakir, O.; Yasar, F.T.; Bozdemir, O.A.; Icli, B.; Akkaya, E.U. “Autonomous Shuttling Driven by an Oscillating Reaction: Proof of Principle in a Cucurbit[7]uril-Bodipy Pseudorotaxane” Org. Lett. 2013, 15, 1012-1015.


    79.       Isik, M; Ozdemir, T.; Turan, I.S.; Kolemen, S.; Akkaya, E.U. “Chromogenic and Fluorogenic Sensing of Biological Thiols in Aqueous Solutions Using BODIPY-Based Reagents” Org. Lett. 2013, 15, 216-219.


    78.       Erbas-Cakmak, S.; Bozdemir, O.A.;  Cakmak, Y.; Akkaya, E.U. “Proof of principle for a molecular 1:2 demultiplexer to function as an autonomously switching theranostic device” Chem. Sci. 2013, 4, 858-862.


    77.       Sozmen, F.; Oksal, B.S.; Bozdemir, O.A.; Buyukcakir, O.; Akkaya, E.U. “Heteroleptic Metallosupramolecular Complexes of Bodipy Dyes as Energy Transfer Cassettes” Org. Lett. 2012, 14, 5286-5289.


    76.       Kostereli, Z.; Ozdemir, T.; Buyukcakir, O.; Akkaya, E.U. “Tetrastyryl-BODIPY-Based Dendritic Light Harvester and Estimation of Energy Transfer Efficiency” Org. Lett. 2012, 14, 3636-3639.


    75.       Duman, S.; Cakmak, Y.; Kolemen, S.; Akkaya, E.U., Dede, Y. “Heavy Atom Free Singlet Oxygen Generation: Doubly Substituted Configurations Dominate S-1 States of Bis-BODIPYs” J. Org. Chem. 2012, 77, 4516-4527.

     

    74.       Expanded Bodipy Dyes: Anion Sensing Using a Bodipy Analog with an Additional Difluoroboron Bridge, Guliyev, R.; Ozturk, S.; Sahin, E.; Akkaya, E.U. Org. Lett. 2012, 14, 1528.

     

    73.              Designing Excited States: Theory-Guided Access to Efficient Photosensitizers for Photodynamic Action, Cakmak, Y.; Kolemen, S.; Duman, S.; Dede, Y.; Dolen, Y.; Kilic, B.; Kostereli, Z.; Yildirim, L. T.; Dogan, A. L.; Guc, D.;  Akkaya, E. U. Angew. Chem. Int. Ed. 2011, 50, 11937-11941.

    72.              Towards Unimolecular Luminescent Solar Concentrators: Bodipy-based Dendritic Energy-Transfer Cascade with Panchromatic Absorption and Monochromatized Emission, Bozdemir, O. A.; Erbas-Cakmak, S.; Ekiz, O. O.; Dana, A.; Akkaya, E. U. Angew. Chem. Int. Ed. 2011, 50, 10907-10912.

     

    71.              From Virtual to Physical: Integration of Chemical Logic Gates, Guliyev, R.; Ozturk, S. Kostereli, Z.; Akkaya, E. U. Angew. Chem. Int. Ed. 2011, 50, 9826-9831. Selected as the frontispiece for the “communications” section.

     

    70.              Optimization of distyryl-Bodipy chromophores for efficient panchromatic sensitization in dye sensitized solar cells, Kolemen, S.; Bozdemir, O. A.; Cakmak, Y.; Barin, G.; Erten-Ela, S.; Marszalek, M.; Yum, J. H.; Zakeeruddin, S. M.; Nazeeruddin, M. K.; Gratzel, M.; Akkaya, E. U. Chem. Sci.  2011, 2, 949.

     

    69.              Selective Hg(II) sensing with Improved Stokes Shift by Coupling ICT Process to Excitation Energy Transfer, Atilgan, S.; Ozdemir, T.; Akkaya, E. U. Org. Lett. 2010, 12, 4792.

     

    68.              Solid-State Dye-Sensitized Solar Cells Using Red and Near IR absorbing Bodipy Sensitizers, Kolemen, S.; Cakmak, Y.; Erten-Ela, S.; Altay, Y.; Brendel, J.; Thelakkat, M.; Akkaya, E. U. Org. Lett. 2010, 12, 3892.

     

    67.              Reaction-based Sensing of Fluoride Ions Using Built-In Triggers for ICT and PET, Bozdemir, O. A.; Sozmen, F.; Buyukcakir, O.; Guliyev, R.; Cakmak, Y.;  Akkaya, E. U. Org. Lett. 2010, 12, 1400-1403.

     

    66.              Selective Manipulation of ICT and PET Processes in Styryl-Bodipy Derivatives: Applications in Molecular Logic and Simultaneous Sensing of Multiple Metal Ions. Bozdemir, O. A.; Guliyev, R.; Buyukcakir, O.; Selcuk, S.; Kolemen, S.; Gulseren, G.; Nalbantoglu, T.; Boyaci, H.; Akkaya, E. U. J. Am. Chem. Soc. 2010, 132, 8029-8036.  JOURNAL COVER Featured on the cover of issue June 16, 2010.

     

    65.              Synthesis of Symmetrical Multichromophoric BODIPY Dyes and Their Facile Transformation into Energy Transfer Cassettes, Bozdemir, O. A.; Cakmak, Y.; Sozmen, F.; Ozdemir, T.; Siemiarczuk, A.; Akkaya, E. U. Chem. Eur. J. 2010, 16, 6346-6351.

     

    64.              Convergent synthesis and light harvesting properties of dendritic boradiazaindacene (BODIPY) appended perylenediimide dyes, Bozdemir, O. A.; Yilmaz, M. D.; Buyukcakir, O.; Siemiarczuk, A.; Tutas, M.; Akkaya, E. U. New J. Chem. 2010, 34, 151-155.

     

    63.              Tetrastyryl-Bodipy Dyes: Convenient Synthesis and Characterization of Elusive Near IR Fluorophores, Buyukcakir, O.; Bozdemir, O. A.; Kolemen, S.; Erbas, S.;  Akkaya, E. U. Org. Lett. 2009, 11, 4644-4667.

     

     

    62.              Design Strategies for Ratiometric Chemosensors: Modulation of Excitation Energy Transfer at the Energy Donor Site, Guliyev, R.; Coskun, A.; Akkaya, E. U. J. Am. Chem. Soc. 2009, 131, 9007-9013.

     

    61.              Non-covalent Functionalized SWNTs as Delivery Agents for Novel Bodipy-based Potential PDT Sensitizers, Erbas, S.; Gorgulu, A.; Kocakusakogullari, Akkaya, E. U. Chem. Comm. 2009, 4956-4958.

     

    60.              Solid-State Emissive BODIPY Dyes with Bulky Substituents As Spacers, Ozdemir, T.; Atilgan, S.; Kutuk, I.; Yildirim, L. T.; Tulek, A.; Bayindir, M.; Akkaya, E. U.  Org. Lett. 2009, 11, 2105-2107.

     

    59.              Novel Molecular Building Blocks Based on the Boradiazaindacene Chromophore: Applications in Fluorescent Metallosupramolecular Coordination Polymers, Bozdemir, O. A.; Buyukcakir, O.; Akkaya, E. U. Chem. Eur. J. 2009, 15, 3830-3838.

     

    58.              Boradiazaindacene (Bodipy)-based building blocks for the construction of energy transfer cassettes, Barin, G.; Yilmaz, M. D.; Akkaya, E. U. Tetrahedron Lett. 2009, 50, 1738-1740.

     

    57.              Phenylethynyl-BODIPY Oligomers: Bright Dyes and Fluorescent Building Blocks, Cakmak, Y.; Akkaya, E. U. Org. Lett. 2009, 11, 85-88.

     

    56.              Thinking Outside the Silicon Box: Molecular AND Logic As an Additional Layer of Selectivity in Singlet Oxygen Generation for Photodynamic Therapy, Ozlem, S.; Akkaya, E. U. J. Am. Chem. Soc. 2009, 131, 48-49. (featured in C & EN News, Science and Technology Concentrates, January 19, 2009)

     

    55.              A sensitive and selective ratiometric near IR fluorescent probe for zinc ions based on the distyryl-bodipy fluorophore, Atilgan, S.; Ozdemir, T., Akkaya, E. U. Org. Lett. 2008, 10, 4065-4067.

     

    54.              Bidirectional Switching of Near IR Emitting Boradiazaindacene Fluorophores, Deniz, E.; Isbasar, G. C.; Bozdemir, O. A.; Yildirim, L. T.; Siemiarczuk, A.; Akkaya, E. U. Org. Lett. 2008, 10, 3401-3403.

     

    53.              A panchromatic boradiazaindacene (BODIPY) sensitizer for dye-sensitized solar cells, Ela-Erten, S.; Yilmaz, M. D.; Icli, B.; Dede, Y.; Icli, S.; Akkaya, E. U. Org. Lett. 2008, 10, 3299-3301.

     

    52.              A Monostyryl-boradiazaindacene (BODIPY) Derivative as Colorimetric and Fluorescent Probe for Cyanide Ions, Ekmekci, Z.; Yilmaz, M. D.; Akkaya, E.U. Org. Lett. 2008, 10, 461-464.

     

    51.              Sensitive fluorescent chemosensor for anions based on a styryl-boradiazaindacene framework, Coskun A.; Deniz, E.; Akkaya, E.U. Tetrahedron Lett. 2007, 48, 5359-5361.

     

    50.              Dipyridyl-substituted boratriaazaindacene as a NIR emitting chemosensor for Hg(II).  Coskun, A; Yilmaz, M. D.; Akkaya, E.U. Org. Lett. 2007, 9, 607-609.

     

    49.              Signal Ratio Amplification via Modulation of Resonance Energy Transfer: Proof of Principle in an Emission Ratiometric Hg(II) Sensor, Coskun, A; Akkaya, E.U. J. Am. Chem. Soc. 2006, 128, 14474-14475.

     

    48.              Dye sensitized artificial photosynthesis in the gas phase over thin and thick TiO2 films under UV and visible light irradiation. Ozcan, O.; Yukruk, F.; Akkaya, E. U.; Uner, D. Appl. Cat. B. Environmental 2007, 71, 291-297.

     

    47.              Water soluble distyryl-boradiazaindacenes as efficient photosensitizers for photodynamic therapy, Atilgan, S.; Ekmekci, Z.; Dogan, A. L.; Guc, D.; Akkaya, E. U. Chem. Commun. 2006, 4398-4399.  (presented as  HOT ARTICLE in ChemCommun web site)

     

    46.              Dye sensitized CO2 reduction over pure and platinized TiO2, Ozcan, O.; Yukruk, F.; Akkaya, E. U.; Uner, D. Topics Catal. 2007, 44, 523-528.

     

    45.              Light Harvesting and Efficient Energy Transfer in a Boron-dipyrrin (BODIPY) Functionalized Perylenediimide Derivative, Yilmaz, M. D.; Bozdemir, O. A.; Akkaya, E. U. Org. Lett. 2006, 8, 2871-2873.

     

    44.              Distyryl-boradiazaindacenes: facile synthesis of novel near IR emitting fluorophores, Dost, Z.; Atilgan, S.; Akkaya, E. U.  Tetrahedron 2006, 62, 8484-8488.

     

    43.              An acenaphthopyrrolone-dipicolylamine derivative as a selective and sensitive chemosensor for group IIB cations, Coşkun, A.; Yılmaz, M. D.; Akkaya, E.U. Tetrahedron Lett.  2006, 47, 3689-3691.

     

    42.              Excimer emission and energy transfer in cofacial boradiazaindacene (BODIPY) dimers built on a xanthene scaffold, Saki, N.; Dinc, T.; Akkaya, E.U. Tetrahedron 2006, 62, 2721-2725.

     

    41.              Unexpected Cyclization of Dipyridyl-glycoluril in the Presence of Formaldehyde and Strong Acid: A New Scaffold with a Potential as a Receptor, Saki, N.; Icli, B.; Cevheroglu, O. J. Inc. Phen. Macrocycl. Chem. 2006, 55,  219-222.

     

    40.              Effective PET and ICT Switching of Boradiazaindacene Emission: A Unimolecular, Emission Mode Molecular Half-Subtractor with Reconfigurable Logic Gates, Coskun, A.; Deniz, E.; Akkaya, E.U. Org. Lett. 2005, 7, 5187-5189.

     

    39.              Ion Sensing Coupled to Resonance Energy Transfer:  A Highly Selective and Sensitive Ratiometric Fluorescent Chemosensor for Ag(I) by a Modular Approach, Coskun, A.; Akkaya, E. U. J. Am. Chem. Soc. 2005, 127, 10464-10465.

     

    38.              Modulation of internal charge transfer (ICT) in a bay region hydroxylated perylenediimide (PDI) chromophore: A chromogenic chemosensor for pH. Yukruk, F.; Akkaya, E. U. Tetrahedron Lett. 2005, 46, 5931-5933.

     

    37.              Cation modulation of dipyrrinone fluorescence: emission ratiometric calcium sensing, Coskun, A.; Deniz, E.; Akkaya, E.U.  J. Mater. Chem. 2005, 15, 2908-2912.

     

    36.              Water soluble green Perylenediimide (PDI) dyes as novel sensitizers for photodynamic therapy, Yukruk, F.; Dogan, A.L.; Canpinar, H.; Guc, D.; Akkaya, E.U. Org. Lett. 2005, 7, 2885-2887.

     

    35.              Synthesis, p-nitrophenolate complexation and competitive anion signaling of a novel calixpyrrole dimer, Saki, N.; Akkaya, E.U. J. Inc. Phen. Macrocycl. Chem. 2005 53, 269-273.

     

    34.              A calixpyridinium-pyranine complex as a selective anion sensing assembly via the indicator displacement strategy, Atilgan, S.; Akkaya, E. U. Tetrahedron Lett. 2004 45, 9269-9271.

     

     

    33.              Three-point recognition and selective fluorescence sensing of L-DOPA., Coskun, A.; Akkaya, E.U. Org. Lett. 2004, 6, 3107-3109.

     

     

    32.      Bifunctional catalysis of ester hydrolysis: novel hydrolytic enzyme models based on xanthene framework, Saki, N.; Akkaya, E.U. J. Mol. Catal. A. Chemical 2004, 219, 227-232.

     

    31.       Difluoroboradiaza-s-indacene dyes as highly selective dosimetric reagents for fluoride anions, Coskun, A.; Akkaya, E.U. Tetrahedron Lett. 2004, 45, 4947-4949.

     

    30.       Differential and substrate selective catalysis by calixarene derivatives with cyclenyl-Zinc(II) modifications at the upper rim, Gulsum Ozturk, Engin U. Akkaya Org. Lett. 2004, 6, 241-243.

     

     

    29.       Novel fluorescent chemosensor for anions via modulation of oxidative PET: A remarkable 25-fold enhancement of emission, Ali Coşkun, Bilge T. Baytekin, Engin U. Akkaya Tetrahedron Lett. 2003, 44, 5649-5651.

     

    28.         Fiber optic sodium and potassium sensing by using a newly synthesized   squaraine dye in PVC matrix. Ertekin, K.; Tepe, M.; Yenigül, B.;   Akkaya, E.U.; Henden, E. Talanta, 2002, 58, 719-727.

     

    27.       Modulation of Boradiazaindacene Emission by Cation Mediated Oxidative PET, Turfan, B.; Akkaya, E.U., Org. Lett. 2002, 4, 2857-2859.

     

    26.       Selective chromogenic response via regioselective binding of cations: A novel approach in chemosensor design, Ataman, D.; Akkaya, E.U. Tetrahedron Lett. 2002, 43, 3981-3983.

     

    25.  Potassium sensing by using a newly synthesized squaraine dye in sol-gel  matrix,   Ertekin, K.; Yenigül, B.; Akkaya, E.U. J. Fluorescence 2002, 12, 263.

     

    24.      Boradiazaindacene appended calix[4]arene: Fluorescence sensing of pH near neutrality, Baki, C. N.; Akkaya, E.U. J. Org. Chem. 2001, 66, 1512.

     

    23.       Remarkable cooperative action of two zinc centers in the hydrolysis of plasmid DNA, Aka, F. N.; Akkaya, M. S.; Akkaya, E.U. J. Mol. Catal. A. Chemical 2001, 165, 291-294.

     

    22.      A Molecular NAND gate based on Watson-Crick base-pairing, Baytekin, H. T.; Akkaya, E.U. Organic Lett. 2000, 2, 1725-1727.

     

    21.       Infrared fluorescence sensing of submicromolar calcium: Pushing the limits of photoinduced electron transfer, Ozmen, B.; Akkaya, E.U. Tetrahedron Lett. 2000, 41, 9185-9188.

     

    20.       Simultaneous determination of cadmium and zinc using a fiber optic device and fluorescence spectrometry, Ertas, N.; Akkaya, E. U.; Ataman, O. Y. Talanta, 2000, 51, 693-699.

     

    19.       Novel squaraine signalling Zn(II) ions: Three-state fluorescence response to a single input , Dilek, G.; Akkaya, E.U. Tetrahedron Lett. 2000, 41, 3721-3724.

     

    18.       A Novel cyclodextrin homodimer with dual-mode substrate binding and esterase activity, Tastan, P.; Akkaya, E.U. J. Mol. Catal. A. Chemical 2000, 157, 261-263.

     

    17.       Red to Near IR Fluorescent Signalling of Carbohydrates, Kukrer, B.; Akkaya, E.U. Tetrahedron Lett. 1999, 40, 9125-9128.

     

    16.       A Novel Lanthanide Complex with Remarkable Phosphodiester Transesterification Activity and DNA-conjugatable Functionality, Baykal, U. Akkaya, M.S., Akkaya, E.U. J. Inc. Phen. 1999, 35, 311.

     

    15.              Remarkable phosphodiester hydrolysis activity of a novel CeIV complex in neutral aqueous solutions, Baykal, U.; Akkaya, M.S.; Akkaya, E.U. J. Mol. Catal. A. Chemical 1999, 145, 309.

     

    14.       An Efficient Synthesis of a Novel Bifunctional Chelating Agent, Erdogan, B.; Akkaya, E.U. Tetrahedron Lett., 1998, 39, 9107.

     

    13.       One-Pot Synthesis of Squaraine Fluoroionophores, Oguz, U.; Akkaya, E.U. J. Org. Chem., 1998, 63, 6059.

     

    12.       Synthesis and Phosphodiester Transesterification Activity of the La(III)-complex of a Novel Functionalized Octadentate Ligand, Baykal, U.; Akkaya, E.U. Tetrahedron Lett., 1998, 39, 5861.

     

    11.       A Squaraine-based Sodium Selective Fluorescent Chemosensor, Oguz, U.; Akkaya, E.U. Tetrahedron Lett., 1998, 39, 5857.

     

     

    10.       Chemosensing in Deep Red: A Squaraine-based Fluorescent Chemosensor for pH, Isgor, Y.G.; Akkaya, E.U. Tetrahedron Lett., 1997, 38, 7417.

     

    9.         A Squaraine-based Near IR Fluorescent Chemosensor for Calcium, Akkaya, E.U.; Turkyilmaz, S. Tetrahedron Lett., 1997, 38, 4513.

     

    8.         One-Pot Synthesis of a Red-Fluorescent Chemosensor from an Azacrown, Phloroglucinol and Squaric Acid: A Simple In-solution Construction of a Functional Molecular Device, Oguz, U.; Akkaya, E.U. Tetrahedron Lett., 1997, 38, 4509.

     

    7.         Simultaneous Determination of Cd and Zn by Fluorescence Spectrometry Using a Novel Reagent and Surfactants, Ertas, N.; Akkaya, E.U.; Ataman, O.Y., Quimica Analytica, 1997, 16, S101.

     

    6.         Styryl-based Wavelength-Ratiometric Probes: A New Class of Fluorescent Calcium Probes with Long Wavelength Emission and a Large Stokes’ Shift, Akkaya, E.U.; Lakowicz, J.R. Analytical Biochem., 1993, 213, 285.

     

    5.         Synthesis and Transacylating Activity of Isomeric Co(III)-cyclodextrin Artificial Metalloenzymes, Akkaya, E.U.; Czarnik, A.W. J. Phys. Org. Chem., 1992, 5, 540.

     

    4.         Synthesis and Characterization of a Reactive Binuclear Co(III) Complex:  Cooperative Promotion of Phosphodiester Hydrolysis, Chung, Y. Akkaya, E.U.; Venkatachalam, T.K.; Czarnik, A.W. Tetrahedron Lett., 1990, 31, 5413.

     

    3.         Chelation Enhanced Fluorescence of Anthrylazamacrocycle Conjugate Probes in Aqueous Solutions, Akkaya, E.U., Huston, M.E.; Czarnik, A.W. J. Am. Chem. Soc., 1990, 112, 3590.

     

    2.         Chelation Enhanced Fluorescence Detection of Non-metal Ions, Huston, M.E.; Akkaya, E.U.; Czarnik, A.W. J. Am. Chem. Soc., 1989, 111, 8735.

     

    1.  Synthesis and Reactivity of Cobalt(III) Complexes Bearing Primary and Secondary Side Cyclodextrin Binding Sites: A Tale of Two CD’s, Akkaya, E.U.; Czarnik, A.W. J. Am. Chem. Soc., 1988, 110, 8553.





       



     

     


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